The evaluation of prophylactic effect of intralesional steroid injection to prevent esophageal stricture after ESD(endoscopic submucosal dissection) of superficial esophageal cancers

The evaluation of prophylactic effect of intralesional steroid injection to prevent esophageal stricture after ESD(endoscopic submucosal dissection) of superficial esophageal cancers - The evaluation of prophylactic effect of intralesional steroid injection to prevent esophageal stricture after ESD(endoscopic submucosal dissection) of superficial esophageal cancers

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005649

Enrollment

Registered

2011-05-27

Start date

2010-09-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial esophageal cancers

Interventions

The weekly group receive 40mg of triamcinolone acetonide weekly The biweekly group receive 40mg of triamcinolone acetonide biweekly

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Relative adaptational lesion for ESD and more than 3/4 luminal circumferencial mucosal defect

Exclusion criteria

Exclusion criteria: 1)Not acceptance to participate in the study 2)Allergy for triamcinolone acetonide 3)Severe DM or adrenal malfunction 4)Inappropriate for this trial

Design outcomes

Primary

Measure	Time frame
To compare the treatment duration between 2 groups (the weekly group receive 40mg of triamcinolone acetonide weekly, the biweekly group receive 40mg of triamcinolone acetonide biweekly )	—

Secondary

Measure	Time frame
Frequency of EBD(endoscopic balloon dilations), Stricture rate, Frequency of adverse events	—

Countries

Japan

Contacts

Public ContactMorita Yoshinori

Kobe University, School fo Medicine Department of Gastroenterology

ymorita@med.kobe-u.ac.jp0783826305

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026