Primary Open-Angle Glaucoma
Conditions
Interventions
None listed
Sponsors
Keio University School of Medicine,Department of Ophthalmology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects were screened for eligibility by means of an ophthalmic examination that included slit-lamp biomicroscopy, funduscopy, gonioscopy, intraocular pressure measurements with Goldmann applanation tonometry, and visual field examination with a static visual field analyzer using the 30-2 Swedish Interactive Threshold Algorithm Standard Strategy (Carl Zeiss Meditec, Dublin, CA) when necessary. POAG was diagnosed on the basis of the presence of the following 3 findings: (1) glaucomatous optic cupping represented by notch formation, generalized enlargement of cupping, senile sclerotic disc or myopic disc, or nerve fiber layer defects; (2) typical glaucomatous visual field defects such as Bjerrum scotoma, nasal step, or paracentral scotoma compatible with optic disc appearance; and (3) open and not occludable angle observed on gonioscopy. All patients with POAG underwent a visual field examination to assess POAG severity. For the purposes of this study, we defined mild POAG as a visual field defect corresponding to a mean deviation (MD) of -6 dB or better in both eyes, moderate POAG as corresponding to a MD of -6 to -12 dB in the worse eye, and severe POAG as a MD of -12 dB or worse in the worse eye.
Exclusion criteria
Exclusion criteria: Subjects with fundus disease such as age-related macular degeneration, prpriferative diabetic retinopathy, or any fundus diease. Subjects who is unable to take informed consent. Subjects who cannot walk without help.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of falls and motor vehicle collisions | — |
Countries
Japan
Outcome results
None listed