The effects of pneumoperitoneum with carbon dioxide insufflation on forehead skin and cerebral blood flows in patients undergoing gynecological laparoscope assisted surgery

The effects of pneumoperitoneum with carbon dioxide insufflation on forehead skin and cerebral blood flows in patients undergoing gynecological laparoscope assisted surgery - Carbon dioxide overexposure itself spare skin and brain blood flows?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000005571

Enrollment

Registered

2011-06-01

Start date

2011-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gynecological laparoscope assisted surgery

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients with ASA physical status I and II undergoing gynecological laparoscope assisted surgeries for benign diseases (myoma uteri, ovarian tumor and cysts) were enrolled.

Exclusion criteria

Exclusion criteria: Excluded criteria were patient's body mass index (BMI)>35 or <18, and patients with diabetes mellitus, hypertension, collagen diseases, skin diseases, and allergies to foods or drugs.

Design outcomes

Primary

Measure	Time frame
The main study observed changes in forehead skin blood flow measured by the laser flowmeter together with cerebral oxymetry (rsO2) at the 9 measuring points including start of surgery, just after start of pneumoperitoneum, just pre- and post TP (-15 degree), 10 and 20 minutes after TP, just pre- and post-postural change, and end of surgery. The supplement study compared the changes in them together with forehead skin temperature between patients pretreated with acetazolamide 5 mg/kg IV and placebo at the commencement of anesthesia.	—

Measure

Time frame

The main study observed changes in forehead skin blood flow measured by the laser flowmeter together with cerebral oxymetry (rsO2) at the 9 measuring points including start of surgery, just after start of pneumoperitoneum, just pre- and post TP (-15 degree), 10 and 20 minutes after TP, just pre- and post-postural change, and end of surgery. The supplement study compared the changes in them together with forehead skin temperature between patients pretreated with acetazolamide 5 mg/kg IV and placebo at the commencement of anesthesia.

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Countries

Japan

Outcome results