Major depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosed as suffering from major depressive disorder according to the DSM-IV 2. Expected to be on continuation/maintenance antidepressant therapy for at least nine months after the patients had responded to acute phase antidepressant therapy and were in partial or full remission, i.e. they no longer fulfilled the diagnostic threshold for major depressive episode 3. Not having undergone electroconvulsive therapy or not having electroconvulsive therapy already planned for the index episode 4. Living with the family for 3 months or longer before participating in this study and being expected to live with the family during the investigation period 5. Having at least one family member living with the patient who was available for family interviews.
Exclusion criteria
Exclusion criteria: 1. Patients were screened with the Mini-Mental Status Examination 11 when dementia was clinically suspected and those scoring 23 or below were excluded. 2. Patients suspected of having organic diseases were examined by head magnetic resonance imaging, and those diagnosed as such were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relapse/recurrence of a major depressive episode | — |
Countries
Japan