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Single-Agent Molecularly Targeted Therapy for Adults with Recurrent Glioblastoma Multiforme: A Meta-Analysis

Single-Agent Molecularly Targeted Therapy for Adults with Recurrent Glioblastoma Multiforme: A Meta-Analysis - Molecularly targeted monotherapy in recurrent GBM

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000005516
Enrollment
1000
Registered
2011-04-27
Start date
2010-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Glioblastoma Multiforme

Interventions

None listed

Sponsors

Kurume University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: An English-language literature search of the PubMed, EMBASE, Proceedings of American Society of Clinical Oncology, Proceedings of European Society of Neuro-Oncology, Proceedings of World Federation of Neuro-Oncology, Proceedings of Society of Neuro-Oncology, and the registry of the U.S. National Institutes of Health clinicaltrials.gov databases, including all publications as of September 2010. All phase II or III trials conducted in 1995 or later were included.

Exclusion criteria

Exclusion criteria: After a review of abstracts, articles were excluded if they did not contain the relevant outcome data or if they selected patients retrospectively based on known outcomes. In the case of different publications describing the same patient cohort, only the most recent publication was used for further analysis.

Design outcomes

Primary

MeasureTime frame
Overall survival

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026