Healthy volunteer, RBD and Parkinson'
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: [healthy volunteer] 50y.o.<=Age<=88y.o., cognitive normal subjects without severe physical complication [Rapid eye movement behavior disorder (RBD)] 50y.o.<=Age<=88y.o., patients diagnosed with RBD according to the International Clasiffication of Sleep Disorders: second edition (ICSD-2) [Westchester.2005] [Parkinson's disease (PD)] 50y.o.<=Age<=88y.o., patients diagnosed with PD according to UK brain bank Parkinson's disease diagnostic criteria [Hughes AJ.1992]
Exclusion criteria
Exclusion criteria: [RBD] [PD] 1.psychiatric complications such as drug abuse 2.other organic brain complications such as symptomatic stroke, PD-related disorders and other neurodegenrative diseases 3.severe physical complications 4.exclude the patients who are recognized as inadequate patients by doctors with resposibility in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantitative measurement of brain dopamine transporter binding and brain acetylcholinesterase activity in PET | — |
Countries
Japan
Contacts
QST Hospital, National Institutes for Quantum and Radiological Clinical Research Support Section