Multicenter retrospective study for trasient abnormal myelopoiesis (JPLSG TAM-10)

Multicenter retrospective study for trasient abnormal myelopoiesis (JPLSG TAM-10) - JPLSG TAM-10

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000005418

Enrollment

Registered

2011-04-15

Start date

2011-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transient abnormal myelopoiesis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria is as follows: 1) Patient is diagnosised as Down syndrome or mosaic Down syndrome. But patients without Down syndrome who has megakaryocytic blast with GATA1 mutation and somatic trisomy 21 are including to this study. 2) Patient is diagnosed with transient abnormal myelopoiesis under 90 das after birth. 3) Registration should be done within 30 days after diagnosis. 4) Diagnosed day should be after the opening day of this study. 5) Written informed concent by patient's guardian should be obtained.

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
Event free survival	—

Secondary

Measure	Time frame
Overall survival Proportion of patients who received chemotherapy Percentage of adverse events Cumulative incidence of progression to acute leukemia	—

Countries

Japan

Contacts

Public ContactEmiko Nishioka

JPLSG TAM committee

officej2@jplsg.jp052-228-7159

Outcome results