Clinical study on taste function and ultramicroscopic observation of regenerated fungiform papillae and nerve ending after reconstruction of the chorda tympani nerve

Clinical study on taste function and ultramicroscopic observation of regenerated fungiform papillae and nerve ending after reconstruction of the chorda tympani nerve - Ultrastructure of regenerated human fungiform papillae

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005390

Enrollment

Registered

2011-04-06

Start date

2010-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Taste dysfunction

Interventions

Severance of chorda tympani nerve

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Case with normal electrogustometric threshold pre-operatively 2. Case with severance of chorda tympani nerve 3. Case with normalization of electrogustometric threshold post-operatively 4. Case without recovery of electrogustometric threshold

Exclusion criteria

Exclusion criteria: Case with abnormal electrogustometric threshold pre-operatively

Design outcomes

Primary

Measure	Time frame
1. Morphological detection of regenerated fungiform taste buds and nerve ending 2. Number of taste buds per papilla	—

Secondary

Measure	Time frame
Normalization of electrogustometric threshold	—

Countries

Japan

Contacts

Public ContactTakehisa Saito

University of Fukui Fuculty of Medicine

takehisa@u-fukui.ac.jp0776-61-3111(2398)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026