Comparison of the effects of cilnidipine and benidipine on urinary excretions of albumin and type-IV collagen in Japanese hypertensive type-2 diabetic patients with nephropathy.

Comparison of the effects of cilnidipine and benidipine on urinary excretions of albumin and type-IV collagen in Japanese hypertensive type-2 diabetic patients with nephropathy. - Comparison of the effects of cilnidipine and benidipine on urinary excretions of albumin and type-IV collagen in Japanese hypertensive type-2 diabetic patients with nephropathy.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005384

Enrollment

Registered

2011-04-06

Start date

2011-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertensive type-2 diabetic patients with nephropathy

Interventions

with cilnidipine for 24 weeks followed with benidipine for 24 weeks with benidipine for 24 weeks followed with cilnidipine for 24 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Japanese hypertensive type-2 diabetic patients with nephropathy with renin-angiotensin system inhibitor and calcium antagonist (cilnidipine, benidipie or other) for more than 3 months without requirement of adding other antihypertensive agents SBP<140 mmHg, DBP<90 mmHg HbA1c < 9.0%

Exclusion criteria

Exclusion criteria: acute illness or malignant tumors drug allergy with pregnant or breast feeding, or candidates with such situations patients who are judged as inappropriate for inclusion by their physicians

Design outcomes

Primary

Measure	Time frame
Changes in urinary excretions of albumin and type-IV collagen between groups with either cilnidipine or benidipine	—

Secondary

Measure	Time frame
Changes in blood pressure and glycemic control	—

Countries

Japan

Contacts

Public ContactTakuma Narita

Akita University Garduate School of Medicine Department of Endocrinology, Diabetes and Geriatric Medicine

narita@med.akita-u.ac.jp018-884-6769

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026