Frequency and the mechanism of RMMA induced by esophageal acidification

Frequency and the mechanism of RMMA induced by esophageal acidification - Frequency and the mechanism of RMMA induced by esophageal acidification

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005350

Enrollment

Registered

2011-03-31

Start date

2011-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bruxism

Interventions

Infusion of an acdic solution into the esophagus (0.1N HCl, multiple infusion) Infusion of a saline into the esophagus (Saline, multiple infusion) stress induced by calculation task reading

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy adult without bruxism

Exclusion criteria

Exclusion criteria: 1. Individual with bruxism 2. Individual with gastro-intestinal disease 3. Individual with temporomandibular disorders 4. Individual with any medication within three months

Design outcomes

Primary

Measure	Time frame
Masticatory muscle activity Frequency of swallowing	—

Secondary

Measure	Time frame
Autonomic nurve activity Esophageal acid clearance Brain activity	—

Countries

Japan

Contacts

Public ContactMika Fukushima

Kagoshima University Graduate School of Medical and Dental Sciences Department of Orthodontics

fukushima@dent.kagoshima-u.ac.jp099-275-6252

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026