Dry eye
Conditions
Interventions
Sponsors
Department of Ophthalmology, Kyoto Prefectural University of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Normal subject (20 persons) without following 1)-4) 2. Aqueous tear deficient dry eye patients and Short BUT type dry eye patients (30 persons). 3. Aqueous tear deficient dry eye patients with following 1),2) and 4) 4. Short BUT type dry eye patients with following 1) and 3) who have not been responsible for conventional instillation treatment. 1) Symptoms (Visual disturbance, Discomfort) 2) Schirmer test (I) <= 5mm 3) Tear film breakup time <= 5 seconds 4) Positive vital dye staining of cornea and conjunctiva (Fluorescein, Lissamine green)(more than 3, maximum=9)
Exclusion criteria
Exclusion criteria: Anyone who is considered to be inappropriate for this study (ex. Any allergic history to Systane Balance, Dry Aid&#174; EX and SoftSantear&#174;, women who are under pregnant or lactation period)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tear film breakup time, corneal and conjunctival epithelial damage score, tear meniscus radius, Schirmer test(I), spreading velocity of tear film lipid layer | — |
Countries
Japan
Contacts
Public ContactNorihiko Yokoi, Takahiro Kurose
Kyoto Prefectural University of Medicine Department of Ophthalmology
Outcome results
None listed