Febrile neutropenia
Conditions
Interventions
Administration of antibiotics (Cefepime)
Administration of antibiotics (Meropenem)
Sponsors
LOGIK(Lung oncology group in Kyushu)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Informed consent is obtained 2. Patient who is judged as an appropriate case by the doctor in charge 3. At least 20 years of age 4. Patient who had lung cancer accompanied by chemotherapy-induced neutropenia with a polymorphonuclear neutrophil count of <1000/mm3 and a temperature of >= 37.5
Exclusion criteria
Exclusion criteria: 1. Patient who is too severely ill 2. A history of cardiac failure, renal failure, or liver damage. 3. A known history of hypersensitivity to cephalosporins 4. A known history of allergy 5. Patient who demonstrated positive for skin reaction test ( if skin reaction test was done) 6. Patient who is not evaluated for response 7. Pregnant or lactating women. 8. Patient administered with sodium valproate 9. Patients administered with prohibiting medication (such as other antibiotics, gamma-globulin, corticosteroid, furosemide) 10.patient who is judged as an inappropriate case by the doctor in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Defervescence at 72 hours, 7 days, 14 days Safety | — |
Countries
Japan
Contacts
Public ContactJunji Uchino
Fukuoka University Department of Respiratory Medicine
Outcome results
None listed