Application of hyaluronic acid and collagen sponge with epidermal growth factor (EGF) for intractable skin ulcers and burn ulcers

Application of hyaluronic acid and collagen sponge with epidermal growth factor (EGF) for intractable skin ulcers and burn ulcers - Application of EGF wound dressing for intractable skin ulcers and burn ulcers

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005264

Enrollment

Registered

2011-03-20

Start date

2011-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intractable skin ulcers, burn ulcers, donor sites of skin grafts and traumatic skin defects

Interventions

EGF wound dressing is used for 6 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who has intractable skin ulcers (diabetic skin ulcers and burn ulcers), donor sites of skin grafts or traumatic skin defects. 2. Patients who agreed with their written informed consent

Exclusion criteria

Exclusion criteria: 1. Patients with hypersensitivity to any of the study drugs 2. Patiests who have a history of malignancy at the wound site. 3. Patients who are considered to be unsuitable for this study by the investigator

Design outcomes

Primary

Measure	Time frame
1. Wound area size 2. Granulation tissue formation 3. Extent of epithelialization 4. Infection 5. Macroscopic appearance	—

Secondary

Measure	Time frame
1. Effectiveness 2. Safety 3. Overall clinical evaluation	—

Countries

Japan

Contacts

Public ContactAkane Yu

Kitasato University School of Medicine Department of Plastic and Aesthetic Surgery

akanenaka@hotmail.com042-778-9074

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026