Effect of synbiotics on oral immunotherapy for food allergy: a randomized study

Effect of synbiotics on oral immunotherapy for food allergy: a randomized study - Synbiotics in oral immunotherapy for food allergy (SYNBOIT trial)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005244

Enrollment

100

Registered

2011-03-20

Start date

2011-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Food allergy

Interventions

Slow oral immunotherapy + synbiotics (1years) Slow oral immunotherapy (1years)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) children (ages 1-5 years) 2) patients with immediate allergic reaction to egg or milk.

Exclusion criteria

Exclusion criteria: Patients who have pronounced anaphylaxis shock. Patients with severe symptoms with food challenge test.

Design outcomes

Primary

Measure	Time frame
Difference of achievement rate in immunotherapy between symbiotic group and control group.	—

Secondary

Measure	Time frame
Occurrence and severity of adverse effect, change of biological marker.	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026