The effect of Sitagliptin on Coronary Flow Reserve in Type 2 Diabetic Patients with Coronary Artery Disease

The effect of Sitagliptin on Coronary Flow Reserve in Type 2 Diabetic Patients with Coronary Artery Disease - The effect of Sitagliptin on Coronary Flow Reserve

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000005238

Enrollment

Registered

2011-03-11

Start date

2011-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetic Patients with Coronary Artery Disease

Interventions

Add-on Stagliptin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Type2 diabetic patients with coronary artery disease.(HbA1c >=6.5% JDS) 2)Age >=20 years, <80 years (Male and Female) 3)A consent form for participating in this study is submitted

Exclusion criteria

Exclusion criteria: 1)Patients with type 1 diabetes 2)Patients receiving Alfa-glycosidase inhibitor, Insulin or Glinide 3)History of severe ketosis, diabetic coma or precoma within 6 months 4)Patients with severe infections, before or after operation, or with serious trauma 5)Patients who are pregnant, breastfeeding or intention to becoming pregnant 6)Patients with exceeding the moderate renal impairment 7)Having allergy to DPP-4 Inhibitor 8)Patients with significant stenosis at major 3 coronary artery or with history for PCI 9)Other patients determined to be inappropriate by physician

Design outcomes

Primary

Measure	Time frame
Coronary flow reserve by coronary flow wire	—

Secondary

Measure	Time frame
1,5-AG, CAVI, FMD, MMP-9, PTX3	—

Countries

Japan

Contacts

Public ContactHiroyasu Uzui

University of Fukui, Faculty of Medical Sciences Division of cardiovascular Medicine

huzui@u-fukui.ac.jp0776-61-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026