Advenced biliary tract cancer
Conditions
Interventions
unilateral drainage
bilateral drainage
Sponsors
Kawasaki Medical Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patients who have biliary tract carcionoma with type2, 3a, 3b, or 4 hilar biliary stricture according to Bismuth's classification and with abnormal liver function tests 2. The liver funstion tests improve after unirateral drainage with transpapillary endoscopic naso-biliary drainage using plastic stents within four weeks. 3. Biliary tract cancer which is histologically or cytologically proven malignancy 4. Atrophy of the liver is not found due to vascular invasion. 5. Unresectable biriary tract cancer over stage 2b according to TNM classification 6. Patients fully understand and are willing to give a written informed consent about participation.
Exclusion criteria
Exclusion criteria: 1. Performance status is 4. 2. ASA calassification is over 3. 3. Informed consent is not achieved. 4. Patients considered ineligible for this study. 5. The prognosis is considered within three months. 6. Patients who recieved additional treatment after initial unilateral drainage with naso-biliary plastic stents 7. Left or right lobe is occupied by the tumor. 8. Transpapillary deployment of metallic stents is not achieved.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| duration from stent deployment to re-intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. over all survival 2. complication rate 3. rate of stent patency at death 4. rate of application of endoscopic re-intervention to first stent occlusion and success rate of the intervention | — |
Countries
Japan
Contacts
Public ContactHironari Kato
Okayama University Hospital Department of gastroenterology and hepatology
Outcome results
None listed