Hypertension
Conditions
Interventions
1)The uploading contents of all meals to the mobile phone site by the subject 2)The measurement of the amount of the day salt intake by the subject 3)The home blood pressure measurement by the subje
Sponsors
Kanetsu hospital
Laboratory of Pharmaceutical Regulatory Science, School of Pharmacy, Nihon University Cyber Cross Japan, Ltd. SRL, Ltd. School of Medicine, Showa University Graduate school of Medicine, Tokyo University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)A adult with prehypertension (SBP 130~139 mmHg and/or DBP 85~89 mmHg) or class I hypertension (SBP 140~159 mmHg and/or DBP 90~99 mmHg). 2)When subjects take antihypertensive drugs, it is controlled enough, and there is not an additional plan during study period. 3)The subjects who do not take the supplements or the health foods which an effect on blood pressure suggests, or are based on a mineral such as calcium during study period. 4)20 years old or older, and under 75 years old 5)Outpatient. 6)The subjects who submit the informed consent of this study 7)The mean of the salt intake that calculated by a salt intake measuring instrument is more than 10.0g/day.
Exclusion criteria
Exclusion criteria: 1)The patients with class III hypertension (SBP >= 180mmHg and/or DBP >= 110mmHg) 2)The patients with secondary hypertension 3)The patients with stroke, myocardial infarction and serious vascular disease to require hospitalization within six months 4)The patients with hepatic dysfunction (the levels of GOT (AST) and GPT (ALT) exceed 3 times of the standard value (facility criteria).) 5)The patients with renal dysfunction (>= CKD Stage III) 6)The patients with heart failure (>= NYHA III) 7)The patients with a malignant tumor or the poor-prognosis illness 8)The patients who judged the principal investigator (or the subinvestigators) to be inappropriate from a medical base
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount and the rate of change of the daily salt intake The amount and the rate of change of the blood pressure (hospital and home) | — |
Secondary
| Measure | Time frame |
|---|---|
| A:The correlation between the daily salt intake and the blood pressure (hospital and home) B:The search of the relations with the blood-pressure that was depressed by sodium restriction and the factors that has an influence on the sodium restriction 1.The subject background 2.The blood pressure and the heart rate 3.The daily salt intake when the subject began the sodium restriction 4.The sodium restriction instruction that combined the mobile phone site 5.The rate of taking prescription drugs (compliance) 6.The weight when the subject began the sodium restriction 7.The blood tests | — |
Countries
Japan
Contacts
Public ContactMotoki Arakawa
School of Pharmacy, Nihon University Laboratory of Pharmaceutical Regulatory Science
Outcome results
None listed