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Sulindac for the prevention of colorectal serrated polyps:A pilot study

Sulindac for the prevention of colorectal serrated polyps:A pilot study - Sulindac for the prevention of colorectal serrated polyps:A pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000005156
Enrollment
30
Registered
2011-03-20
Start date
2011-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal serrated polyps

Interventions

sulindac(300mg/day)

Sponsors

Department of gastroenterology and oncology institute of health biosciences the university of tokushima graduate school
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Candidate patients have to meet all the following inclusion criteria to participate in the study. #Patients with at least one colorectal serrated polyps as confirmed by histological diagnosis. #Patients with known history of all endoscopic treatments of colorectal tumor. #Patients who have undergone total colonoscopy at least one.

Exclusion criteria

Exclusion criteria: #Patients currently taking antithrombotics such as Bayasupirin,Bufferin,Panaldine,Warfarin and Persantin. #Patients with familial colorectal adenoma # Patients with a history of treatment of gastric or duodenal ulcer(those with successful eradication of Helicobacter pylori and ulcer resolution at S2 are allowed to participate in the study) #Patients with any existing cancer at the time of participate in the study # Patients with known allergy to NSAIDs # Patients currently taking anticancer drugs #Women who are or may be pregnant during the study period. # Patients currently taking NSAIDs at least 3 times weekly, for example,as analgesic.

Design outcomes

Primary

MeasureTime frame
Number and size of colorectal serrated polyps two years later

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026