Study to investigate the mechanism of steroid insensitivity in severe asthmatic patients

Study to investigate the mechanism of steroid insensitivity in severe asthmatic patients - Study to investigate the steroid insensitivity in severe asthma

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000005106

Enrollment

Registered

2011-03-01

Start date

2011-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchial asthma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Adult patients with bronchial asthma who receive outpatient treatment in our clinic 2)Patients who gave consult to the study 3)Healty subjects

Exclusion criteria

Exclusion criteria: 1)Patients with pulmonary infectious diseases, or interstitial pneumonia, or Lung cancer 2)Patients who are considered inappropriate by physicians in charge

Design outcomes

Primary

Measure	Time frame
Levels of biomarkers, which are related to steroid insensitiviry, in induced sputum	—

Secondary

Measure	Time frame
1)Expression of asthma related biomarkers in blood 2)Exhaled nitric oxide level 3)Indices of pulmonary function 4)Indices of airway responsiveness	—

Countries

Japan

Contacts

Public ContactTomoko Tajiri

Kyoto University Graduate School of Medicine Department of Respiratory Medicine

tomokot@kuhp.kyoto-u.ac.jp075-751-3830

Outcome results