Cholecystitis, Cholangitis, severe Acute pancreatitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inpatient aged 20 or over regardless of gender
Exclusion criteria
Exclusion criteria: (1) Cases with severe cardiac, hepatic, renal function disorder (2) Cases with a history of allergy to B-lactam antibiotics (carbapenems,cephems, penicillins, etc) (3) Cases pregnant, lactating or suspected of being pregnant (4) Cases which therapeutic response of B-lactam antibiotics can not be expected (caused by virus, mycoplasma, chlamydia and fungus) (5) Cases treated with sodium valproate or with central nervous system damage such as epilepsia (6) Cases which need combined usage of diuretic such as furosemide (7) Cases with improvement by previous treatment of antimicrobial agent (8) Cases with similar infectious episode of ineffective treatment with carbapenem antibiotics (9) Other cases which doctor in charge regard inadequate to include in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Causative bacteria and antimicrobial susceptibility before and after antimicrobial administration Clinical response and safety of day 3 and day 7 after Biapenem is administered | — |
Countries
Japan
Contacts
Nagaoka Chuo Hospital Koseiren,Niigata-Ken internal medicine