Food hypersensitivity,Food allergy
Conditions
Interventions
To take small amount of egg powder masked with corn powder once daily for 25-28 weeks
To take corn powder as placebo once daily for 25-28 weeks
Sponsors
National Center for Child Health and Development
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patients who keep complete elimination of egg from their diet 2)Patients who were confirmed as having egg allergy by double blind placebo controlled food challenge test 3)Egg white-specific IgE-positive patients 4)Patients whose family are cooperative enough to adhere to the protocol of this study
Exclusion criteria
Exclusion criteria: 1)Patients without immediate-type reaction to egg 2)Patients with uncontrolled asthma, atopic dermatitis or urticaria 3)Corn allergy patients 4)Patients who have treatment history or plan with omalizumab
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The result of double -blind placebo controlled food challenge test of egg after 25-28 weeks intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)The threshold change of egg allergen dose to provoke immediate reaction before and after this intervention 2)The change of egg specific antibody serum concentration before and after this intervention 3)Incidence of patients who experience allergic reaction due to adverse effect of this intervention 4)Onset number of allergic reaction due to adverse effect of this intervention in each case | — |
Countries
Japan
Contacts
Public ContactYuki Tsumura
National Center for Child Health and Development Division of Allergy
Outcome results
None listed