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Effects of systemic administration of black currants anthocyanins on visual field deterioration of patients with glaucoma

Effects of systemic administration of black currants anthocyanins on visual field deterioration of patients with glaucoma - Effects of black currants anthocyanins on glaucomatous optic neuropathy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000004961
Enrollment
50
Registered
2011-01-26
Start date
2006-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

An intervention group was administrated with 50mg anthocyanins once daily for 24 months. A control group was administrated with placebo once daily for 24 months.

Sponsors

Department of Ophthalmology, Sapporo Medical University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)clinically defined glaucoma petients. 2)MD deterioration within a recent one year was less than -0.5 dB under suitable and stable IOP levels obtained by anti-glaucoma drops. 3) MD at baseline was better than -12 dB in the better eye in Humphrey visual field 30-2 test. 4) best-corrected visual acuity of 20/30 or more in at least one eye. 5) no history of cataract surgery until one year previously. 6) no ocular diseases other than glaucoma or an early to mild senile cataract that would not influence the Humphrey visual field testing. 7) reliable performance on the Humphrey visual field testing. 8) no use of other supplements including anthocyanins.

Exclusion criteria

Exclusion criteria: Any patients did not satisfy one of above criteria.

Design outcomes

Primary

MeasureTime frame
visual field deterioration

Secondary

MeasureTime frame
changes of ocular blood flows and intraocular pressures

Countries

Japan

Contacts

Public ContactHisae Nakayama

Sapporo Medical University Department of Ophthalmology

011-611-2111(3435)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026