Randomized controlled study of Flush knife versus Mucosectome in endoscopic submucosal dissection for superficial esophageal cancer

Randomized controlled study of Flush knife versus Mucosectome in endoscopic submucosal dissection for superficial esophageal cancer - Randomized study comparing ESD device.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004942

Enrollment

Registered

2011-01-25

Start date

2011-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial esophageal cancer

Interventions

ESD using Flush knife ESD using Mucosectome

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Superficial esophageal squamous cell carcinoma 15mm - 50mm in diameter, circumferential spread 1/2 or less.

Exclusion criteria

Exclusion criteria: 1)Patients with past history of operation, chemotherapy or radiotherapy for esophageal cancer. 2)Local recurrence after endoscopic resection. 3)Patients with iodine allergy. 4)Lesions those are extending into pharyngoesophageal junction or esophago-gastric junction. 5)Patients with esophageal lesion in the area of reflux esophagitis. 6)Patients with hematological abnormality. 7)Patients with severe organ failure 8)Patients who have been judged as inappropriate for this study.

Design outcomes

Primary

Measure	Time frame
Procedure time of submucosal dissection	—

Countries

Japan

Contacts

Public ContactHiromitsu Kanzaki

Osaka Medical Center for Cancer and Cardiovascular Diseases Gastrointestinal Oncology

kanzai-hi@mc.pref.osaka.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026