patients on anti-thrombotic therapy who need gastrointestinal endoscopy procedure using biopsy forceps.
Conditions
Interventions
group A:to perform gastric biopsy while continuing antithrombotic agents(warfarin, aspirin, thienopyridine derivatives).
group B:to perform gastric biopsy under discontinuation of antithrombotic agen
Sponsors
Shinshu University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: adult patients who need gastrointestinal endoscopy, and may require endoscopic procedures using biopsy forceps.
Exclusion criteria
Exclusion criteria: 1)without agreement 2)PT-INR>3.0 in warfarin taking patients(within 1 Month before procudere) 3)taking dual antiplatelet therapy(both aspirin and thienopyridine delivatives)(patients under discontinuation of thienopyridine delivatives before biopsy procedure can be enrolled). 4)receiving both anticoagulant and antiplatelet therapy(patients with discontinuation of antiplatelet agents or warfarin before biopsy procedure can be enrolled). 5)taking antiplatelet agents other than aspirin or thienopyridine derivatives. 6)within 12months after drug eluting stent placement. 7)taking warfarin for DVT. 8)other serious conditions, pregnency, overt bleeding tendency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)the prevalence and severity of gastric bleeding during gastric biopsy, and the prevalence of gastric breeding which requires hemostatic therapy. 2)The prevalence and severity of postoperative gastric bleedig after gastric biopsy, and the prevalence of the breeding which requires hemostatic therapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)the prevalence and severity of thromboembolic events. | — |
Countries
Japan
Contacts
Public ContactHiroki Kasai
Shinshu University School of Medicine Department of Cardiovascular Medicine
Outcome results
None listed