Patients with suspected lung cancer
Conditions
Interventions
Spontaneous sputum cytology specimens were collected from each subject for 3 days after registration. On each day during the subsequent 3-day period, each subject was asked to inhale nebulized 10% hyp
Sponsors
National Hospital Organization Asahikawa Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with suspected lung cancer based on the detection of an abnormal opacity on the chest X-ray. Written informed consent
Exclusion criteria
Exclusion criteria: (1) patients with uncontrolled asthma, (2) patients with severe hepatopathy, nephropathy, cardiac disease or hematological disease, or other serious complications, (3) pregnant or possibly pregnant women, and (4) other patients judged by the physician as being unsuitable candidates for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sputum expectoration rate | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Cytological examination of sputum induced by 10% hypertonic saline 2. Analysis of adverse events arising from the inhalation of 10% hypertonic saline 3. Testing of the lung carcinoma cells for EGFR gene mutation in sputum cytology-positive cases and comparison of the test results between spontaneous and induced sputum specimens 4. Questionnaire survey of the patients. | — |
Countries
Japan
Contacts
Public ContactYuka Fujita
National Hospital Organization Asahikawa Medical Center Respiratory Medicine
Outcome results
None listed