An exploratory investigation of the biomarker for senescence and arteriosclerosis in renal transplant donors and recipients.

An exploratory investigation of the biomarker for senescence and arteriosclerosis in renal transplant donors and recipients. - An exploratory investigation of the biomarker for senescence and arteriosclerosis in renal transplant donors and recipients.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000004905

Enrollment

Registered

2011-01-24

Start date

2010-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recipients and donors in living-kidney transplantation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are scheduled living-kidney transplantation as recipients or donors in Kagawa University Hospital and agreed with the study

Exclusion criteria

Exclusion criteria: 1)Kidney transplant from cadaver donors or brain-dead donors. 2)Patients who are under 16 years-old 3)Patients without agreement 4)Patients inadequate for the study

Design outcomes

Primary

Measure	Time frame
1)AGT (urine and serum),soluble (pro) renin receptor (urine and serum) and plasma AMDA: 0,12,36,60 months 2)Senescence-associated beta galactosidase and arteriosclerosis in donated kidney or allograft: 0,12,36,60 months	—

Secondary

Measure	Time frame
1)Cr and eGFR in donors and recipients: 0,6,12,24,36,48,60 months 2)CAVI and central BP: 0,12,36,60 months 3)urinary albumin, proteinuria and urinary occult blood: 0,6,12,24,36,48,60 months 4)patient survival rates, allograft survival rates and cardiovascular events: 0-60months 5)BP: 0,6,12,24,36,48,60 months	—

Countries

Japan

Contacts

Public ContactTadashi Sofue

Kagawa University, Faculty of Medicine Department of Cardiorenal and Cerebrovascular Medicine

sofue@med.kagawa-u.ac.jp087-891-5111

Outcome results