non small and non squamous lung cancer
Conditions
Interventions
Pemetrexed, Carboplatin
Sponsors
Department of Thoracic Surgery, University of Tsukuba
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Initial chemottherapy 2.ECOG performance status0-1 3.Stage IIor III after complete resection 4.Age of 20 years or older 5.Laboratory parameters obtained before registation WBC count:>4000/uL, <12000/uL neutrophil count:>2000/uL Platelet count:>10*10000/uL Hemoglobin:>9.5g/dL GOT,GPT:<100 IU/L Total bilirubin:<2.0mg/dL PaO2:>60 torr creatinine:<1.5mg/dL 6.Anticipated life expectancy of at least 3 months 7.Capable to registrate in 30days after surgery 8.Capable to stay in the hospital 9.Obtained informed consent
Exclusion criteria
Exclusion criteria: 1.Interstitial pneumonia or pulmonary fibrosis on Chest Xray 2.Unstable pleural effusion formation 3.Superior vena cava syndrome 4.Uncotrolled diabetes mellitus, hypertension, liver dysfunction, angina pectoris, and acute myocardial infarction 5.Severe infection, a sign of severe infection 6.Grade2 or worse peripheral nerve disorder at the time of enrollment 7.Regular user of NSAIDs 8.Pregnant woman, lactating woman, woman of child-bearing potential, woman who wish to pregnancy 9.Severe drug allergy 10.Severe complication 11Other inadequate reasons 12.New lesion that is recognized before enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| feasibility study (4 courses) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1-year recurrence-free survival | — |
Countries
Japan
Contacts
Public ContactMitsuaki Sakai
University of Tsukuba Department of Thoracic Surgery
Outcome results
None listed