A double-blind placebo-controlled clinical trial of botulinum toxin type A injection therapy in patients with Japanese cedar pollinosis 2011

A double-blind placebo-controlled clinical trial of botulinum toxin type A injection therapy in patients with Japanese cedar pollinosis 2011 - Effect of Botulinum Toxin Type A Therapy in Patients with Japanese cedar pollinosis (E-BOAT study 3)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004862

Enrollment

Registered

2011-01-14

Start date

2011-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Japanese cedar pollinosis

Interventions

One ml (20U) of botulinum toxin type A is injected into each inferior turbinate during the season of Japanese cedar pollinosis. Loratadine (10 mg) and /or fluticason propionate nasal sprays can be use

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)a history of Japanese cedar pollinosis 2)CAP-RAST against Japanese cedar pollen >=2

Exclusion criteria

Exclusion criteria: 1)pregnancy or possibility of pregnancy 2)history of heart disease 3)history of glaucoma 4)history of prostate hypertrophy 5)history of neuro-muscular disease 6)history of stroke 7)accompanying acute rhinitis or sinusitis 8)use of any anti-allergy drugs at the beginning of the study 9)history of nasal surgery 10)prominent deviation of the nasal septum

Design outcomes

Primary

Measure	Time frame
Symptom score, Medication score, QOL estimation, Rhinomanometry	—

Secondary

Measure	Time frame
Adverse events	—

Countries

Japan

Contacts

Public ContactAtsushi Kamijo

University of Yamanashi Department of Otorhinolaryngoloty, Head and Neck Surgery

akamijyo@yamanashi.ac.jp055-273-6769

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026