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Efficacy of Ischemic Postconditioning Combined with Thrombus Aspiration Therapy in Patients with ST-segment. Elevation Myocardial Infarction.

Efficacy of Ischemic Postconditioning Combined with Thrombus Aspiration Therapy in Patients with ST-segment. Elevation Myocardial Infarction. - iPost study

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000004812
Enrollment
116
Registered
2011-01-02
Start date
2010-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with ST-elevation AMI admitted or referred to the Coronary Care Unit of the Division of Cardiology of St.Lukes.International Hospital in Japan, after successful percutaneous coronary intervention and who are eligible for cardiac MRI will be enrolled prospectively. Informed consent will be obtained from each patient before enrollment in the study, according to the approved protocol.

Interventions

ipost procedure group
n=58 standard treatment group
n=58

Sponsors

St.Luke's International Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion Criteria 1)Subject must have ST-segment Elevation Myocardial Infarction 2)Subject must be 20 years of age or older. 3)histry of cardiac-ischemia-related symptoms <12 hours prior to initial presentation. 4)clinical decision was made to treat with PCI. 5)Subject must be willing and able to give informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria will be previous AMI, candidate of CABG cardiogenic shock or Killip 4, rescue angioplasty after thrombolytic therapy, evidence of coronary collaterals in the risk area, TIMI flow grade 3 before intervention, inability to lay flat due to severe cardiac heart failure/respiratory insufficiency, pregnancy, known existence of a life threatening disease, and inability to give informed consent. In addition, exclusion criteria will be any contraindication to undergo CMR, such as severe renal dysfunction implanted metallic objects;cardiac pacemakers and/or implantable cardioverter defibrillator or any other type of electronic devices, or any other contraindication to CMR. Patients with newly placed intracoronary stents will be included.

Design outcomes

Primary

MeasureTime frame
ST segment resolution

Countries

Japan

Contacts

Public ContactTakuya Watanabe

St.Luke's International Hospital Cardiology Department

watataku@luke.or.jp03-3541-5151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026