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A Double-Blind, Randomized Study of Minocycline for the Decision-Making Process in Young Adult Healthy Volunteer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000004803
Enrollment
100
Registered
2010-12-29
Start date
2010-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult Males

Interventions

100mg minocycline capsule, morning and evening, 4 days, controlled groups placebo drugs same dose and same days. Placebo capsule, morning and evening, 4 days

Sponsors

Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University
Lead Sponsor
Waseda University
Collaborator

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1.Healthy adult male 2.20 years old to 29 years old 3.Those who can obtain informed consent

Exclusion criteria

Exclusion criteria: 1. Those who ever have side effects by antibiotics including minocycline 2. Those who have severe disease in heart, liver or kidney. 3. Those who have a tendency to develop allergy 4. Those who have ever diagnosed psychiatric disorders. 5. Those who are judged not appropriate to this study by medical doctor in charge.

Design outcomes

Primary

MeasureTime frame
1: Trust game with an anonymous stranger 2: Trust games with 40 face pictures. 3: Task that subject try to detect cheaters in the past trust games

Secondary

MeasureTime frame
Self-reported questionnaire including 1 STAI, 2 TCI, and 3 General Trust scales.

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026