aspiration pneumonia
Conditions
Interventions
Decide the duration of antibiotics therapy based on the level of procalcitonin on admission.
Decide the duration of the antibiotics therapy according to standard protocol. Antibiotics use is continue
Sponsors
Hamamatsu Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Hospital admitted patients with a diagnosis of aspiration pneumonia by clinical history and radiorogical appearance. (2) One month or more passes from the last pneumonia treatment for the relapse cases. (3) The ventilator use is not scheduled for the pneumonia treatment.
Exclusion criteria
Exclusion criteria: (1) Known severe allergy to any drugs (2) Sepsis, severe infectious disease (3) Fatal and severe underlying disease, malignancy, COPD, heart failure and so on. (4) Patients who cannot safely receive cessation of eating or hydration as a treatment for aspiration pneumonia because of dementia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To prove the noninferiority of procalcitonin-guided protocol about the adverse outcomes of death, recurrent of aspiration pneumonia within 2 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of antibiotics exposure and adverse effect from antibiotics. | — |
Countries
Japan
Outcome results
None listed