Prospective observational study to establish a method to predict the outcome of CKD patients by combined medical information by interview, imaging, and pathological findings

Prospective observational study to establish a method to predict the outcome of CKD patients by combined medical information by interview, imaging, and pathological findings - Prediction of renal outcome by nephron number estimated in CKD patients (PRONEP)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000004784

Enrollment

600

Registered

2011-01-01

Start date

2011-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease (CKD)

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: CKD patients received renal biopsy (Informed concent should be obtained before renal biopsy. If impossible, IC obtained until one month after renal biopsy can be available)

Exclusion criteria

Exclusion criteria: 1. Unilateral kidney, severe unilateral kidney atrophy, functionally unilateral kidney 2.patients with malignancy (if they are free over one year without no medication to the malignant disease, they are possible to attend this study)

Design outcomes

Primary

Measure	Time frame
Primary end-point (composite end-point): total mortality, renal death, cerebro-cardiovascular event (ischemic heart disease, cerebral hemorrhage, cerebral infarction), 50% reduction in eGFR	—

Secondary

Measure	Time frame
decline rate of eGFR	—

Countries

Japan

Contacts

Public ContactToshiyuki Imasawa

National Hospital Organization Chiba-East Hospital Division of Nephrology, Diabetes, and Endocrinology

imasawa@cehpnet.com043-261-5171

Outcome results