The effect of heart rate control with beta-blocker in the acute phase of myocardial infarction on hemodynamic and functional outcomes.

The effect of heart rate control with beta-blocker in the acute phase of myocardial infarction on hemodynamic and functional outcomes. - The effect of heart rate control in the acute phase of myocardial infarction on hemodynamic and functional outcomes.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004782

Enrollment

Registered

2010-12-24

Start date

2010-12-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction

Interventions

Landiolol,Carvedilol

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)first episode of myocardial infarction (2)ST-elevation myocardial infarction (3)admission to hospital within 12 hours of symptom onset (4) heart rate greater than 90 beats/min on admission (5) emergent primary percutaneous coronary intervention

Exclusion criteria

Exclusion criteria: (1)cardiogenic Shock (2)severe deterioration of liver function (3)history of beta-blocker or amiodarone treatment (4)history of side effects or contraindication of beta-blocker (5)hypersensitivity to trial medicine (6)doctor's decision not to register to this regimen

Design outcomes

Primary

Measure	Time frame
(1) estimated infarct size (2) left ventricular function (left ventricular ejection fraction ) (3)incidence of arrhythmia (especially atrial fibrillation , ventricular tachycardia and ventricular fibrillation).	—

Secondary

Measure	Time frame
(1) survival rate (2) reperfusion injury (ie, malignant ventricular arrhythmia , re-elevation of ST-segment and worsening of chest pain after reperfusion) (3)cardiovascular events (ie, cardiac death, nonfatal infarction, re-hospitalization because of cardiac disease, revascularization)	—

Countries

Japan

Contacts

Public ContactYOHEI SOTOMI

Sakurabashi Watanabe Hospital Division of Cardiovascular Medicine

06(6341)8651

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026