Study of the effect of nutrition management on gastrointestinal mucosa and absorption after esophagectomy in esophageal cancer patient

Study of the effect of nutrition management on gastrointestinal mucosa and absorption after esophagectomy in esophageal cancer patient - Study of the effect of nutrition management after esophagectomy

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004777

Enrollment

Registered

2011-04-01

Start date

2011-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

Total parental nutrition enteral nutrition

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) histlogically confirmed esophageal cancer 2) planning to undergo transthoracic esophagectomy and stomach reconstruction 3) WBC: 3000 /mm3>=, =<12000/mm3 and NE: >=1500 mm3 and PLT: >=100000 /mm3 and Hb: >=9.5 g/dL and GOT, GPT: < 1.5 times of institutional upper limit and T-Bil: =<1.5 g/dL and ALP: < 2.5 times of institutional upper limit and Cr: =<1.5 mg/dL and Alb: >=2.8g/dL 4) Written informed concent

Exclusion criteria

Exclusion criteria: 1) history of receiving gastrectomy 2) taking trace element 3) liver disease, mental disease, convulsive seizure, seizure disorder, heart disease, hemoglobinopathy, hemophilia, uncontrolled diabetes mellitus, autoimmune disease 4) history of severe adverse event due to ELNEOPA(R) or RACOL(R) 5) contraindication to ELNEOPA(R) or RACOL(R) 6) pregnancy 7) judged inadequate to this study by chief doctor

Design outcomes

Primary

Measure	Time frame
Change ratio of diamin oxidase (DAO) activity on the day before operation and 3rd and 7th day after operation	—

Secondary

Measure	Time frame
Change of serum albumin, total protein and trace element concentration on the day before operation and 3rd and 7th day after operation	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026