Individual difference of folate metabolism caused by genetic polymorphisms and its improvement by a folate-fortified food (folic acid fortified bread).

Individual difference of folate metabolism caused by genetic polymorphisms and its improvement by a folate-fortified food (folic acid fortified bread). - Improvement of mutants of folate metabolism by folic acid-fortified bread.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004774

Enrollment

Registered

2011-05-31

Start date

2009-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depressive state

Interventions

folic acid-fortified bread intake group control bread intake group

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: healthy Japanese women

Exclusion criteria

Exclusion criteria: patients, supplement taker, drug taker.

Design outcomes

Primary

Measure	Time frame
serum folate, serum homocysteine and CES-D depression score.	—

Secondary

Measure	Time frame
Intake of all nutrients, general blood biochemistry	—

Countries

Japan

Contacts

Public ContactYasuo Kagawa

Kagawa Nutrition University Faculty of Nutrition

kagawa@eiyo.ac.jp049-282-3618

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026