The evaluation of usefulness of peppermint oil solution as an antispasmodic drug for esophagogastroduodenoscopy.

The evaluation of usefulness of peppermint oil solution as an antispasmodic drug for esophagogastroduodenoscopy. - The evaluation of usefulness of peppermint oil solution as an antispasmodic drug for esophagogastroduodenoscopy.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004710

Enrollment

8000

Registered

2010-12-12

Start date

2007-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophagogastric disorder

Interventions

A total of 8269 EGD procedures were carried out in Mitoyo General Hospital, Kagawa prefecture and Tsuyama Central Hospital, Okayama prefecture in Japan from March 2007 to September 2010. Peppermint oi

reg

Nippon Boehringer Ingelheim, Hyogo, Japan) was administered to the 6063 patients (Group HB) Glucagon (GL) (Glucagon G Novo&amp

Novo Nordisk Pharma Ltd., Tokyo, Japan ) was administered to the 157 patients (Group GL) 156 patients (Group NO) carried out procedure without antispasmodic agents

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients who are carried out EGD procedure

Exclusion criteria

Exclusion criteria: Exclusion criteria were clinical evidence of severe diseases such as American Society of Anesthesiologists (ASA) classification of 4 or 5 at the time of procedure, peppermint allergy, and pregnancy or lactation.

Design outcomes

Primary

Measure	Time frame
The efficacy of antispasmodic scores was evaluated between the non-elderly patients and elderly patients	—

Secondary

Measure	Time frame
safety	—

Countries

Japan

Contacts

Public ContactAtsushi Imagawa

Mitoyo General Hospital Department of Gastroenterology

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026