The effect of perioperative use of synbiotics in reducing infectious complications after surgery for esophageal cancer

The effect of perioperative use of synbiotics in reducing infectious complications after surgery for esophageal cancer - The effect of perioperative use of synbiotics in reducing infectious complications after surgery for esophageal cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004704

Enrollment

Registered

2010-12-13

Start date

2007-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical cases of esophageal cancer that receive esophagectomy

Interventions

Yakult BL Seichoyaku (Yakult Honsha, Tokyo, Japan) galactooligosaccharides (Oligomate S-HP, Yakult Honsha) BIOFERMlN-R POWDER

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with esophageal cancer who fulfilled the criteria of this study and agreed with the enrollment in this study

Exclusion criteria

Exclusion criteria: patients who reject to be enrolled in this study patients who do not fulfill the criteria of this study

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative infectious complications	—

Secondary

Measure	Time frame
Inflammatory response (WBC, CRP, duration of SIRS), Abdominal symptoms(diarrhea, abdominal pain, interruption of enteral nutrition),fecal microflora, fecal organic acid, Bacterial translocation(endotoxin and bacteria in portal vein)	—

Countries

Japan

Contacts

Public ContactKoji Tanaka

Osaka Medical Center for Cancer and Cardiovascular Disease Department of surgery

06-6972-1181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026