Sepsis
Conditions
Interventions
Tramadol 2mg/kg is administered intramuscularly after induction of anesthesia. Since then, same dose of tramadol is administered iteratively every five hours until discharge from the intensive care un
Sponsors
Japanese Red Cross Society Wakayama Medical Center Department of Anesthesiology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: After obtaining written informed consent from the patients' next of kin, ASA physical status 1 - 3 patients with generalized peritonitis who are scheduled to undergo the surgery are prospectively enrolled in this study. P1 A normal healthy patient P2 A patient with mild systemic disease P3 A patient with severe systemic disease P4 A patient with severe systemic disease that is a constant threat to life P5 A moribund patient who is not expected to survive without the operation P6 A declared brain-dead patient whose organs are being removed for donor purposes
Exclusion criteria
Exclusion criteria: 1) Age of younger than 18 years 2) Pregnancy 3) Allergy to scheduled drugs 4) Previous history of severe kidney and/or liver disease 5) Previous sulfonylurea use 6) Current use of anticonvulsant drugs 7) Inappropriate patients for study judged by the physicians
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The norepinephrine requirement during and after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Organ dysfunction score, infusion volume, urinary output, and cardiovascular drugs requirement | — |
Countries
Japan
Contacts
Public ContactHiroshi Iranami
Japanese Red Cross Society Wakayama Medical Center Department of Anesthesiology
Outcome results
None listed