Post-ERCP pancreatitis
Conditions
Interventions
Diclofenac group is administered with 50 mg of rectal diclofenac 30 min before ERCP with saline infusion (for patients weighing less than 50 kg, the dose of diclofenac was reduced to 25 mg).
Control
Sponsors
Saga Prefectural Hospital KOSEIKAN
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who are planned ERCP.
Exclusion criteria
Exclusion criteria: Patients with acute or chronic pancreatitis. Patients with a history of endoscopic sphincterotomy. Patients who are diagnosed peptic ulcer disease. Patients with a history of aspirin-induced asthma. Patients with rectal diseases. Patients who are treated with triamterene. Pregnant and breast-feeding women. Patients who had taken NSAIDs during preceding week. Patients with a history of hypersensitivity to NSAIDs. Patients with a severe renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The occurrence of PEP as defined by the criteria of Cotton as the development of abdominal pain and elevation of serum amylase level greater than three times the upper normal limit within 24 hours after ERCP | — |
Countries
Japan
Contacts
Public ContactTaiga Otsuka
Saga Prefectural Hospital KOSEIKAN Hepatobiliary and Pancreatic Medicine
Outcome results
None listed