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Multicenter study on strain rate versus myocardial velocity for assessment of left ventricular relaxation and filling pressure (SMAP study)

Multicenter study on strain rate versus myocardial velocity for assessment of left ventricular relaxation and filling pressure (SMAP study) - Strain rate versus myocardial velocity for assessment of left ventricular relaxation and filling pressure (SMAP study)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000004625
Enrollment
220
Registered
2010-12-01
Start date
2010-01-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure

Interventions

None listed

Sponsors

Hokkaido University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with angina pectoris, suspected angina pectoris, or prior myocardial infarction, patients with dilated or hypertrophic cardiomyopathy, and patients with hypertension who is developing heart failure. Patients with adequate echocardiographic image quality.

Exclusion criteria

Exclusion criteria: Patients with heart rhythm other than sinus rhythm, patients with relevant left-sided valvular heart disease, patients after mitral or aortic valve replacement or mitral annular plasty, or patients with receiving hemodialysis.

Design outcomes

Primary

MeasureTime frame
To evaluate the correlations between myocardial velocity index (e'), flow propagation velocity (Vp), strain rate index (ESR) and time constant (tau) or LV filling pressure.

Secondary

MeasureTime frame
To compare the accuracy for estimating LV relaxation and filling pressure between the measuring methods of e', Vp, and ESR.

Countries

Japan

Contacts

Public ContactSatoshi Yamada

Hokkaido University Graduate School of Medicine Department of Cardiovascular Medicine

syamada@med.hokudai.ac.jp011-706-6974

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026