A trial on the effects of gastric-acid inhibiting drug on treatment of sleep bruxism

A trial on the effects of gastric-acid inhibiting drug on treatment of sleep bruxism - A trial on the effects of gastric-acid inhibiting drug on treatment of sleep bruxism

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004577

Enrollment

Registered

2010-11-18

Start date

2010-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep Bruxism

Interventions

1. Rabeprazole administration (10mg, 7-days, once a day, before dinner) 2. Washout period 3. Placebo administration (7-days, once a day, before dinner) 1. Placebo administration (7-days, on

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient with sleep bruxism

Exclusion criteria

Exclusion criteria: 1. Individual with secondary sleep bruxism 2. Individual with sleep disorder except sleep bruxism 3. Individual with severe gastro-intestinal disease 4. Individual with any medication within three months

Design outcomes

Primary

Measure	Time frame
1. Frequency of sleep bruxism episodes 2. Masticatory muscle activity during sleep	—

Secondary

Measure	Time frame
1. Frequency of tooth grinding noises 2. Sleep-stage distribution 3. Frequency of micro-arousals	—

Countries

Japan

Contacts

Public ContactShouichi Miyawaki

Kagoshima University, Graduate School of Medical and Dental Sciences Department of Orthodontics

miyawaki@dent.kagoshima-u.ac.jp099-275-6252

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026