cT1~T4a esophageal cancers without distant metastasis
Conditions
Interventions
chemotherapy FAP doxorubicin 35 mg/m2/day day1 iv cisplatin 70 mg/m2/day day1 iv 5-fluorouracil 700 mg/m2/day day1-7 civ Every 28 days for 2 cycles After completing treatment, surgical operati
Sponsors
Department of Gastroenterologial Surgery, Graduate School of Medicine,Osaka University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Histologically proven squamous cell carcinoma of the esophagus 2)cT1~4a esophageal cancers without distant metastasis 3)Aged 20 yeara old 4) ECOG PS of 0~2 5) no previous treatment of esophageal cancer 6)adequate organ functions 7) written informed consent
Exclusion criteria
Exclusion criteria: 1)Patients who are unable to tolerate the general anesthesia. 2) Simultaneous or metachronous double cancers 3)with a history of severe allergic reaction against medicines 4) Pregnant or lactating women or women of childbearing potential 5)doctor's decision not to register to this regimen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| two-year disease free survival rate | — |
Countries
Japan
Contacts
Public ContactMakoto Yamasaki
Graduate School of Medicine,Osaka University Department of Gastroenterologial Surgery
Outcome results
None listed