atopic dermatitis, allergic sensitization
Conditions
Interventions
Proactive treatment with emollients (emollient is regularly applied to the whole surface of baby'
s skin at least once a day)
Reactive treatment with emollients (emollient is used only when the parents consider the baby'
s skin dry)
Sponsors
National Center for Child Health & Development
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Infants within the first week after birth (2) High risk infants from atopic dermatitis (family history) (3) Infants without treatment with corticosteroids (4) Infants whose parents gave informed consent
Exclusion criteria
Exclusion criteria: (1) Infants treated with corticosteroid ointment (except genital and anal area) (2) Infants with skin lesions such as dyskeratosis or bullosis diagnosed by specialists in dermatology (3) Small-for-gestational-age (<37 weeks) (4) Infants with hepatic disease, convulsion, cardiac disease, hemophilias, diabetes and auto immune diseases (5) Inappropriate cases evaluated by doctors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The original description in the English version was incorrectly translated. The original description of primary outcome measure in Japanese (the left column) should have been translated as "cumulative rate of incidence of atopic dermatitis and/or eczema by temporal observation". | — |
Secondary
| Measure | Time frame |
|---|---|
| a) specific IgE antibodies b) transepidermal water loss(TEWL) c) stratum corneum water concentration d) stratum corneum pH e) Staphylococcus aureus on skin f) Onset of allergic diseases such as asthma and food allergy | — |
Countries
Japan
Contacts
Public ContactKenta Horimukai
National Research Institute for Child Health & Development Department of Allergy
Outcome results
None listed