Study of the relationship between analgesic effect buprenorphine and genetic polymorphism of OPRM1

Study of the relationship between analgesic effect buprenorphine and genetic polymorphism of OPRM1 - Study of the relationship between analgesic effect buprenorphine and genetic polymorphism of OPRM1

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004538

Enrollment

Registered

2010-11-10

Start date

2010-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy volunteer

Interventions

administration of buprenorphine administration of buprenorphine

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: BMI: 18kg/m2<, <26kg/m2 capable of understanding and adhering to the protocol genotype of OPRM1: 118AA or 118GG

Exclusion criteria

Exclusion criteria: liver dysfunction renal dysfunction ECG abnormality drug dependence drug allergy

Design outcomes

Primary

Measure	Time frame
pain threshold	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026