HCC larger than 3cm
Conditions
Interventions
Combination therapy of RFA with hepatic arterial infusion group
RFA-alone group
Sponsors
Osaka city University Graduate School of Medicine Department of Hepatotlogy
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: I.Patients with primary hepatocellular carcinoma diagnosed by clinical or histological(angiography, CT, etc.) study II.Hepatocellular carcinoma larger than 3cm, technically possible for radiofrequency ablation (except cases of liver resection), aim to complete cure or mass reduction III.Organ function is maintained. The following clinical and laboratory criteria must be satisfied. - Child-Pugh classification A or B patients - Degree of liver failure (Liver damage) A or B patients - Platelet count: more than 30,000 / mm3 IV.Patients are expected to survive more than three months from start of treatment at least V.General conditions ECOG (Japan Clinical Oncology Group) Performance Status 0,1, or 2 VI.Patients obtained writtten informed consent
Exclusion criteria
Exclusion criteria: I.Patients who are considered not to participate in the study by physicians II.Patients with moderate or severe infections III.Patients with uncontrolled diabetes or obstruction IV.Pregnancy, nursing, or woman who may become pregnant V.Patients with a history of hypersensitivity to drugs or contrast agents containing iodine VI.Patients with a history of myocardial infarction within 3 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local recurrence and prognosis | — |
Countries
Japan
Contacts
Public ContactShuji Iwai
Osaka City University Graduate School of Medicine Department of Hepatotlogy
Outcome results
None listed