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Prevention of residual neuromuscular blockade with sugammadex in patients received general anesthesia

Prevention of residual neuromuscular blockade with sugammadex in patients received general anesthesia - Prevention of residual neuromuscular blockade with sugammadex

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000004522
Enrollment
25
Registered
2010-11-08
Start date
2010-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases which need operation under general anesthesia

Interventions

conditions. Either inhalational anesthesia or TIVA is allowed. 2. Tracheal intubation is done after adequate dose of rocronium is injected. 3. Intraoperative rocuronium useage is determined by the
0.9, the reversal with sugammadex is considered once agein and the respiratory condition is checkd. When the reversal is done once again, another TOF ratio is measured.

Sponsors

Tokyo Neuromuscular Meeting
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients, aged 20 or over (ASA phisical status 1-3) and who is operated under general anesthesia using rocuronium as neuromuscular blocking agent and sugammadex as neuromuscular reversal agent.

Exclusion criteria

Exclusion criteria: Patients who have a history of hypersensitivity to rocuronium and bromide. Patients who have a history of hypersensitivity to sugammadex. Patients who have myasthenia gravis and myasthenic syndrome.

Design outcomes

Primary

MeasureTime frame
The number of patients whose TOF ratio <0.9 after tracheal extubation

Secondary

MeasureTime frame
1. Existence or nonexistence of pulmonary or other complication after surgery 2. Total rocuronium dose 3. Time from extubation to measurement of TOF ratio 4. Time from latest rocuronium use to extubation 5. Time from administration of sugammadex to extubation 6. The difference of TOF ratio among the ages and the anesthetic managements

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026