Post-cardiac arrest syndrome
Conditions
Interventions
None listed
Sponsors
Tsuyama Central Hospital Emergency and Critical Care Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients resuscitated after out-of-hospital cardiac arrest. 2. Patients scheduled for therapeutic hypothermia after return of spontaneous circulation (indications: systolic blood pressure >= 90 mmHg, motor response on Glasgow coma scale <= 5, and at least one intact brain stem reflex). 3. Patients for whom intracranial pressure monitoring was required for assessing and treating brain edema until the rewarming.
Exclusion criteria
Exclusion criteria: 1. Patients with hypotension (systolic blood pressure not maintained at >= 90 mmHg after resuscitation). 2. Patients without any brain stem reflex after resuscitation (i.e., pupils are dilated, light reflex is lost, and spontaneous breathing is absent). 3. Patients with intracranial space-occupying lesions(e.g., brain tumor, intracranial hematoma, and subarachnoid hemorrhage). 4. Patients who are pregnant. 5. Patients with immunodeficiency. 6. Rejection by the person with parental authority.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in intracranial pressure during rewarming. Glasgow Coma Scale scores at 1 week after resuscitation. Glasgow Pittsburgh cerebral performance categories and overall performance categories at 1 month after resuscitation. Mortality rates at 1 month after resuscitation. | — |
Countries
Japan
Contacts
Public ContactNaito Hiromichi
Tsuyama Central Hospital Emergency and Critical Care Center
Outcome results
None listed