Effect of pomegranate juice on the pharmacokinetics of midazolam in healthy volunteers.

Effect of pomegranate juice on the pharmacokinetics of midazolam in healthy volunteers. - Pomegranate juice - midazolam interaction study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004459

Enrollment

Registered

2010-10-29

Start date

2006-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Interventions

Subjects consume 200 mL of pomegranate juice every day for 14 days, and receive midazolam (0.015 mg/kg) on day 14. After more than 1 week wash-out periods, the subjects consume 200ml of bottle water e

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adult

Exclusion criteria

Exclusion criteria: Smoker

Design outcomes

Primary

Measure	Time frame
pharmacokinetics of midazolam	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026