Major depression
Conditions
Interventions
TMS are performed with a frequency of 10Hz, trains of 6s, inter-train-intervals of 60s, 15 trains per session, 2 sessions per day on 10 working days.
Sponsors
Reserch Center for Innovative Oncology National Cancer Center Hospital East
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients: 1)are now under treatment in National Cancer Center Hospital East 2)are at least 20 years old and over 3)have a moderate or severe major and minor depressive episode meeting DSM-4 criteria 4)are not able to take antidepressants
Exclusion criteria
Exclusion criteria: Patients: 1)who is not able to understand this study because of dementia, delirium, or other cognitive disorder 2)have brain metastasis 3)have neurological illness (e.g. epilepsy, meningitis) 4)had a history of convulsions 5)have a risk of epilepsy checked by the EEG 6)had previous neurosurgery with implants of metal 7)have pacemaker 8)attempt suicide or have the idea of suicide 9)fall into a stupor 10)have psychotic depression 11)had a history of failed response to electroconvulsive therapy 12)are depressed by organic illness or medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAM-D | — |
Secondary
| Measure | Time frame |
|---|---|
| MADRS,VAS,CGI | — |
Countries
Japan
Contacts
Public ContactAsao Ogawa
Reserch Center for Innovative Oncology National Cancer Center Hospital East Psycho Oncology Division
Outcome results
None listed