Effects of beta-blockers for prevention of atrial fibrillation after open heart surgery

Effects of beta-blockers for prevention of atrial fibrillation after open heart surgery - Effects of beta-blockers for prevention of atrial fibrillation after open heart surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004418

Enrollment

100

Registered

2010-10-20

Start date

2010-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension with open heart surgery(valvular disease, coronary artery bypass graft)

Interventions

Bisoprolol is given from 2.5mg per day, and are increased aim at HR&lt

70bpm until the day before operation. Carvedilol is given from 2.5mg per day, and are increased aim at HR&lt

70bpm until the day before operation.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: hypertension patient with open heart surgery(valvular disease, coronary artery bypass graft)

Exclusion criteria

Exclusion criteria: (1)contraincication of drug (2)EF<30% (3)HR<55bpm (4)past history of myocardial infarction with in 2 weaks (5)previously atrial fibrillation (6)the patient received beta-blockers

Design outcomes

Primary

Measure	Time frame
the onset of atrial fibrillation until post operative day 10	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026